此次《文明帝國 4》採用全 3D 圖形引擎製作,擁有包括中國在內等至少 18 種民族文化供玩家來選用,並導入領導人、偉人、宗教等系統,同時亦支援多人連線對戰及團隊合作模式,還提供玩家社群地圖編輯工具,讓玩家可以製作新遊戲模組以增加遊戲樂趣;遊戲中另收錄超過 70 種過場影片及動畫,更詳細情形可參考 2K Games《文明帝國 4》遊戲官方網站上資訊。
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